In head and neck cancers, the most common causative form of the cancers I squamous cell carcinoma. These types of cancers in head and neck region are named as head and neck squamous cell carcinomas (HNSCC) and are caused by few risk factors such as smoking tobacco, alcohol intake and human papilloma virus (HPV) infection. The advancements in the cancer treatment are helping not only in the treatment also in the screening of the cancers. Though there are the treatments available, there are situations where the patients with HNSCC suffer with the reoccurrences and also sometimes patients drive with the poor survival. In this review, causatives, symptoms, the latest advancements for treating the HNSCC patients and screening procedures are discussed in this short review which would give a path for the researchers to continue their studies.